Elmarco Talks | Engineering Electrospun Fibers for Biomedical Functionalization
In biomedical electrospinning, fiber performance depends on more than
the mat itself. Alex Brunelle of LifeSprout showed how fiber properties affect downstream functionalization and integration with hydrogel systems.
This webinar was broadcast live on 27 October 2026. We are now preparing the recording for our YouTube channel. Subscribe so you never miss another Elmarco Talks webinar.
From Electrospinning to Functionalization
Electrospinning can produce fiber mats for a wide range of biomedical devices, but for many, the mat is only the starting point. For biomedical applications, downstream performance can depend on both the surface chemistry and the fiber characteristics created during electrospinning.
Using LifeSprout’s work with biodegradable PCL fibers as a practical example, Alex Brunelle will explain how fiber mat attributes can influence the efficiency of surface functionalization and integration with hydrogel systems.
What We Learned
- Key considerations when integrating biodegradable PCL fibers with hydrogel systems
- Which fiber mat attributes matter when planning subsequent surface modification
- Critical electrospinning parameters that can affect later functionalization workflows
“The success of functionalizing electrospun fibers is shaped long before surface treatment begins. The characteristics of the electrospun mat influence how it behaves in every downstream step.”
Alex Brunelle, Process Engineer II, LifeSprout
Meet Alex Brunelle
Alex Brunelle is a Process Engineer II at LifeSprout. He holds an MS in Bioengineering from the University of California, Riverside, where he focused on tissue engineering and electrospun biomaterials. His graduate work included developing a hydrogel-integrated electrospun scaffold for a single-step cell seeding and encapsulation process.
Since joining LifeSprout in 2018, Alex has helped establish the manufacturing processes for Lumina™ fiber production. He now leads the scale-up of electrospinning technologies from early development toward commercial production.
About LifeSprout
LifeSprout is a Baltimore-based regenerative aesthetics and tissue reconstruction company founded on Johns Hopkins research. The company develops injectable biostimulatory materials designed to look, feel, and behave like living tissue.
Its lead product, Lumina™, combines immediate volumization with tissue regeneration. The company recently completed a 119-patient clinical trial in Europe and obtained its CE mark.
